Censor.NET reports citing ВВС.
Yi Wang's comments come as the U.S. voices increasing concern at North Korea's development of nuclear weapons and deploys a Navy carrier group off the Korean peninsula.
China, North Korea's only backer, fears conflict could cause the regime to collapse and problems on its border.
"One has the feeling that a conflict could break out at any moment. I think that all relevant parties should be highly vigilant with regards to this situation. We call on all parties to refrain from provoking and threatening each other, whether in words or actions, and not let the situation get to an irreversible and unmanageable stage," Wang said.
Foreign Minister Wang Yi added if war occurred there could be no winner.
North Korean Vice Foreign Minister Han Song Ryol on Friday blamed U.S. President Donald Trump for building up tensions on the Korean Peninsula with his "aggressive" words and tweets.